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Dr. Marianna Grinberg

Statistische Methoden in der Genetik und Chemometrie

Kontakt

Marianna Grinberg
Fakultät Statistik
Technische Universität Dortmund
44221 Dortmund


Sprechzeiten

nach Vereinbarung

 

Studium

  • Master (Statistik), Technische Universität Dortmund, 2013
    Thema: Klassifizierung von toxikologischen Substanzen anhand von hochdimensionalen genetischen Daten

 

Wissenschaftliche Tätigkeiten

  • Seit Oktober 2013: wissenschaftliche Mitarbeiterin an der TU Dortmund

 

Arbeitsgebiete

  • Analyse von Genexpressionsdaten
  • Überlebenszeitanalyse
  • Metaanalyse
  • Toxicogenomik

Publikationen

  • G. Pallocca, J. Nyffeler, X. Dolde, M. Grinberg, G. Gstraunthaler, T. Waldmann, J. Rahnenführer, A. Sachinidis and M. Leist. Impairment of human neural crest cell migration by prolonged exposure to interferon-beta. Arch. Toxicol., Apr 2017.
  • M. Grinberg, D. Djureinovic, H. R. Brunnstrom, J. S. Mattsson, K. Edlund, J. G. Hengstler, L. La Fleur, S. Ekman, H. Koyi, E. Branden, E. Stahle, K. Jirstrom, D. K. Tracy, F. Ponten, J. Botling, J. Rahnenführer and P. Micke. Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters. Mod. Pathol., Mar 2017.
  • Rosemarie Marchan, Bettina Büttner, Jörg Lambert, Karolina Edlund, Iris Glaeser, Meinolf Blaszkewicz, Gregor Leonhardt, Lisa Marienhoff, Darius Kaszta, Moritz Anft, Carsten Watzl, Katrin Madjar, Marianna Grinberg, Eugen Rempel, Roland Hergenröder, Silvia Selinski, Jörg Rahnenführer, Michaela S Lesjak, Joanna D Stewart, Cristina Cadenas and Jan G. Hengstler. Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma. Cancer Research, 2017. [DOI]
  • V. Shinde, S. Perumal Srinivasan, M. Henry, T. Rotshteyn, J. Hescheler, J. Rahnenführer, M. Grinberg, J. Meisig, N. Bluthgen, T. Waldmann, M. Leist, J. G. Hengstler and A. Sachinidis. Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells. Stem Cell Res Ther, vol. 7 no. 1, page 190, Dec 2016.
  • M. Schwaiger, M. Grinberg, D. Moser, J. C. Zang, M. Heinrichs, J. G. Hengstler, J. Rahnenführer, S. Cole and R. Kumsta. Altered Stress-Induced Regulation of Genes in Monocytes in Adults with a History of Childhood Adversity. Neuropsychopharmacology, vol. 41 no. 10, pages 2530-2540, Sep 2016.
  • V. Shinde, L. Hoelting, S. P. Srinivasan, J. Meisig, K. Meganathan, S. Jagtap, M. Grinberg, J. Liebing, N. Bluethgen, J. Rahnenführer, E. Rempel, R. Stoeber, S. Schildknecht, S. Forster, P. Godoy, C. van Thriel, J. A. Gaspar, J. Hescheler, T. Waldmann, J. G. Hengstler, M. Leist and A. Sachinidis. Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests. Archives of Toxicology, pages 1-26, May 2016.
  • L. Hoelting, S. Klima, C. Karreman, M. Grinberg, J. Meisig, M. Henry, T. Rotshteyn, J. Rahnenführer, N. Blüthgen, A. Sachinidis, T. Waldmann and M. Leist. Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants. Stem Cells Transl Med, vol. 5 no. 4, pages 476-487, Apr 2016.
  • G. Pallocca, M. Grinberg, M. Henry, T. Frickey, J. G. Hengstler, T. Waldmann, A. Sachinidis, J. Rahnenführer and M. Leist. Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration. Archives of Toxicology, vol. 90 no. 1, pages 159-180, Jan 2016.
  • Anna-Maria Stock, Franziska Klee, Karolina Edlund, Marianna Grinberg, Seddik Hammad, Rosemarie Marchan, Cristina Cadenas, Bernd Niggemann, Kurt S Zänker, Jörg Rahnenführer, Marcus Schmidt, Jan G Hengstler and Frank Entschladen. Gelsolin Is Associated with Longer Metastasis-free Survival and Reduced Cell Migration in Estrogen Receptor-positive Breast Cancer. Anticancer Res., vol. 35 no. 10, pages 5277-5285, Oct 2015.
  • Eugen Rempel, Lisa Hoelting, Tanja Waldmann, Nina V. Balmer, Stefan Schildknecht, Marianna Grinberg, John Antony Das Gaspar, Vaibhab Shinde, Regina Stober, Rosemarie Marchan, Christoph van Thriel, Julia Liebing, Johannes Meisig, Nils Blüthgen, Agapios Sachinidis, Jörg Rahnenführer, Jan G. Hengstler and Marcel Leist. A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch. Toxicol., vol. 89 no. 9, pages 1599-1618, Sep 2015.
  • Johanna S.M. Mattsson, Bengt Bergman, Marianna Grinberg, Karolina Edlund, Millaray Marincevic, Karin Jirström, Fredrik Pontén, Jan G. Hengstler, Jörg Rahnenführer, Mats G. Karlsson, Christina Karlsson, Gisela Helenius, Johan Botling, Patrick Micke and Miklos Gulyas. Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compartment-specific evaluation of tumor and stromal cell expression. Cancer Lett., vol. 356 no. 2 Pt B, pages 837-845, Jan 2015.
  • M. Grinberg, R. M. Stober, K. Edlund, E. Rempel, P. Godoy, R. Reif, A. Widera, K. Madjar, W. Schmidt Heck, R. Marchan, A. Sachinidis, D. Spitkovsky, J. Hescheler, H. Carmo, M. D. Arbo, B. van de Water, S. Wink, M. Vinken, V. Rogiers, S. Escher, B. Hardy, D. Mitic, G. Myatt, T. Waldmann, A. Mardinoglu, G. Damm, D. Seehofer, A. Nussler, T. S. Weiss, A. Oberemm, A. Lampen, M. M. Schaap, M. Luijten, H. van Steeg, W. E. Thasler, J. C. Kleinjans, R. H. Stierum, M. Leist, J. Rahnenführer and J. G. Hengstler. Toxicogenomics directory of chemically exposed human hepatocytes. Arch. Toxicol., vol. 88 no. 12, pages 2261-2287, Dec 2014.
  • I. Sicking, K. Edlund, E. Wesbuer, V. Weyer, M. J. Battista, A. Lebrecht, C. Solbach, M. Grinberg, J. Lotz, G. Hoffmann, J. Rahnenführer, J. G. Hengstler and M. Schmidt. Prognostic influence of pre-operative C-reactive protein in node-negative breast cancer patients. PLoS ONE, vol. 9 no. 10, page e111306, 2014.